MTX1 Polyclonal antibody, PBS Only

• 

  WB analysis using 15529-1-AP (same clone as 15529-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15529-1-AP (MTX1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15529-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 15529-1-AP (same clone as 15529-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15529-1-AP (MTX1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15529-1-PBS in a different storage buffer formulation.

• 

  IP experiment of MCF-7 using 15529-1-AP (same clone as 15529-1-PBS)

  IP result of anti-MTX1 (IP:15529-1-AP, 4ug; Detection:15529-1-AP 1:700) with MCF-7 cells lysate 1280ug. This data was developed using the same antibody clone with 15529-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

MTX1 Polyclonal Antibody for WB, IP, Indirect ELISA

Cat No. 15529-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, Indirect ELISA

Synonyms

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Product Information

15529-1-PBS targets MTX1 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag7685

  Product name: Recombinant human MTX1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 75-435 aa of BC001906

  Sequence: YVGHLWMGRRPPSPEARGPVPRSSAASRARRSLASPGISPGPLTATIGGAVAGGGPRQGRAEAHKEVFPGQRVGKMAAPMELFCWSGGWGLPSVDLDSLAVLTYARFTGAPLKVHKISNPWQSPSGTLPALRTSHGEVISVPHKIITHLRKEVHTFWIDTKNYVEVTRKWYAEAMPFPLNFFLPGRMQRQYMERLQLLTGEHRPEDEEELEKELYREARECLTLLSQRLGSQKFFFGDAPASLDAFVFSYLALLLQAKLPSGKLQVHLRGLHNLCAYCTHILSLYFPWDGAEVPPQRQTPAGPETEEEPYRRRNQILSVLAGLAAMVGYALLSGIVSIQRATPARAPGTRTLGMAEEDEEE

• Full Name: metaxin 1
• Calculated Molecular Weight: 51 kDa
• Observed Molecular Weight: 35 kDa
• GenBank Accession Number: BC001906
• Gene Symbol: MTX1
• Gene ID (NCBI): 4580
• RRID: AB_2148416
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q13505
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

METAXINs are proteins located in the outer membrane of the mammalian mitochondrion. METAXIN 1 was characterized firstly and was found to play a role in the import of mitochondrial precursor proteins. It may also play a role in the assembly of b-barrel proteins into the outer membrane METAXIN1 was reported to be essential for survival of the postimplantation mouse embryo. METAXIN 1 has multiple transcripts. Several isoforms of METAXIN 1 exist due to the alternative splicing, with the predicted MW of 51, 48 and 36 kDa, respectively. Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane and form complex in the mitochondrion outer membrane.