Anti-Human NKp46/NCR1 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of human PBMCs using 98340-1-RR (same clone as 98340-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human NKp46/NCR1 Rabbit RecAb (98340-1-RR, Clone: 242549D12) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human NCAM1/CD56. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98340-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98340-1-RR (same clone as 98340-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human NKp46/NCR1 Rabbit RecAb (98340-1-RR, Clone: 242549D12) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98340-1-PBS in a different storage buffer formulation.

NKp46/NCR1 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98340-1-PBS

Clone No.242549D12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

NCR 1, Natural killer cell p46-related protein, LY94, hNKp46, CD335

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Product Information

98340-1-PBS targets NKp46/NCR1 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: natural cytotoxicity triggering receptor 1
• Calculated Molecular Weight: 34kDa
• GenBank Accession Number: /
• Gene Symbol: NCR1
• Gene ID (NCBI): 9437
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O76036-1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).