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CoraLite® Plus 488-conjugated NR3C2 Polyclonal antibody

NR3C2 Polyclonal Antibody for IF

Host / Isotype

Rabbit / IgG


human, mouse




CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-21854


MCR, Mineralocorticoid receptor, MLR, MR, NR3C2

Tested Applications

Positive IF detected inHepG2 cells

Recommended dilution

Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-21854 targets NR3C2 in IF applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NR3C2 fusion protein Ag16410
Full Name nuclear receptor subfamily 3, group C, member 2
Calculated Molecular Weight 984 aa, 107 kDa
Observed Molecular Weight 94-110 kDa
GenBank Accession NumberBC111758
Gene Symbol NR3C2
Gene ID (NCBI) 4306
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Nuclear receptor subfamily 3 group C member 2 (NR3C2), also known as Mineralocorticoid receptor (MCR or MR), is a member of the steroid/thyroid /retinoic nuclear hormone receptor superfamily that has been shown to activate gene transcription in response to aldosterone binding. Regulation of the mineralocorticoid receptors occurs through either receptor down-regulation (negative autoregulation) or hormone-mediated upregulation (positive autoregulation). MCR association with HSP 90 appears to be required for hormone binding to MCR and subsequent MCR activation.


Product Specific Protocols
IF protocol for CL Plus 488 NR3C2 antibody CL488-21854Download protocol
Standard Protocols
Click here to view our Standard Protocols