Rac1 Antibody 3 Publications

Mouse Monoclonal| Catalog number: 66122-1-Ig |CloneNo.: 4A4B11

Featured Product KD/KO validated

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Freight/Packing

Con: 105 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
HSCT6 cells, NIH/3T3 cells, human brain tissue, HEK-293 cells, RAW 264.7 cells, HL-60 cells

Positive IP detected in:
HL-60 cells

Positive IHC detected in:
human colon cancer tissue

Positive IF detected in:
NIH/3T3 cells, HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Calculated molecular weight:
21 kDa

Observed molecular weight:
21 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RAC1

Synonyms
MIG5, p21 Rac1, RAC1, RAC1b, Ras like protein TC25, TC 25, TC25
Background

RAC1b, also named as TC25, belongs to the small GTPase superfamily and Rho family. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, it binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles.


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