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S100A14 Polyclonal antibody
S100A14 Polyclonal Antibody for IF, IHC, IP, WB, ELISA
Cat no : 10489-1-AP
Validation Data Gallery
|Positive WB detected in
|MCF-7 cells, rat stomach tissue
|Positive IP detected in
|Positive IHC detected in
|human breast cancer tissue, human colon cancer tissue, human gliomas tissue, human ovary tumor tissue, human skin tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in
|Western Blot (WB)
|WB : 1:500-1:2000
|IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
|IHC : 1:50-1:500
|IF : 1:200-1:800
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
10489-1-AP targets S100A14 in WB, IP, IHC, IF, CoIP, ELISA applications and shows reactivity with human, rat samples.
|Host / Isotype
|Rabbit / IgG
|S100A14 fusion protein Ag0757
|S100 calcium binding protein A14
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
The S100 family is a multifunctional group of EF-hand type calciumbinding proteins. S100A14 protein (previously known as BCMP84, S100A15) is a recently identified member of the S100 family. It is differentially expressed in a number of different human malignancies like ovary, breast, uterus, kidney, rectum and colon cancers, and esophageal and oral squamous cell carcinomas (OSCCs).
|Product Specific Protocols
|WB protocol for S100A14 antibody 10489-1-AP
|IHC protocol for S100A14 antibody 10489-1-AP
|IF protocol for S100A14 antibody 10489-1-AP
|IP protocol for S100A14 antibody 10489-1-AP
|Click here to view our Standard Protocols
The role of S100A14 in epithelial ovarian tumors.
S100A14 suppresses metastasis of nasopharyngeal carcinoma by inhibition of NF-kB signaling through degradation of IRAK1.
Int J Cancer
S100A14 is a novel independent prognostic biomarker in the triple-negative breast cancer subtype.
Cell Death Dis
Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer.
Am J Cancer Res
A new 7-gene survival score assay for pancreatic cancer patient prognosis prediction.
Eur J Cancer
S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9.