Product Information
16901-1-PBS targets SEC11C in applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag10442 Product name: Recombinant human SEC11C protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-192 aa of BC009703 Sequence: MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRES Predict reactive species |
| Full Name | SEC11 homolog C (S. cerevisiae) |
| Calculated Molecular Weight | 192 aa, 22 kDa |
| Observed Molecular Weight | 16-22 kDa |
| GenBank Accession Number | BC009703 |
| Gene Symbol | SEC11C |
| Gene ID (NCBI) | 90701 |
| RRID | AB_3741898 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BY50 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
SEC11C (Signal peptidase complex catalytic subunit SEC11C), also known as SPC21. It is located in the Endoplasmic reticulum membrane. Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum 1. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids. The molecular weight of SEC11C is 22 kDa. It has been reported that its molecular weight is 16kDa (PMID: 38183983).
