SETX Polyclonal antibody, PBS Only

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• SETX Polyclonal antibody, PBS Only (13837-1-PBS)

• 

  WB analysis using 13837-1-AP (same clone as 13837-1-PBS)

  Various lysates were subjected to Tris-Acetate gel system followed by western blot with 13837-1-AP (SETX antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13837-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary cancer using 13837-1-AP (same clone as 13837-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 13837-1-AP (SETX antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13837-1-PBS in a different storage buffer formulation.

SETX Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 13837-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

ALS4, AOA2, EC:3.6.4.-, KIAA0625, SCAR1

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Product Information

13837-1-PBS targets SETX in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag4785

  Product name: Recombinant human SETX protein

  Source: e coli.-derived, T-HIS

  Tag: 6*His

  Domain: 575-930 aa of BC032600

  Sequence: LVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAIIKTCDKNYRHDAVKILKLKPVLQRSLTHPPTIAPEGSRPQGGLPSSKLDSGFAKTSVAASLYHTPSDSKEITLTVTSKDPERPPVHDQLQDPRLLKRMGIEVKGGIFLWDPQPSSPQHPGATPPTGEPGFPVVHQDLSHIQQPAAVVAALSSHKPPVRGEPPAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSETHHTRRNSRWDKRTLEQEDSSSKKRKLL

• Full Name: senataxin
• Calculated Molecular Weight: 2677 aa, 303 kDa
• Observed Molecular Weight: 300 kDa
• GenBank Accession Number: BC032600
• Gene Symbol: SETX
• Gene ID (NCBI): 23064
• RRID: AB_3085425
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q7Z333
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SETX is involved in DNA double-strand breaks damage response generated by oxidative stress (PMID:17562789). It might also plays a role in the development and maturation of germ cells.