SLC25A1 Monoclonal antibody
SLC25A1 Monoclonal Antibody for WB,ELISA
Host / Isotype
Mouse / IgG3
Reactivity
Human, Mouse, Rat
Applications
WB,ELISA
Conjugate
Unconjugated
CloneNo.
1F11A3
Cat no : 66771-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | Jurkat cells, HEK-293 cells, HST-C6 cells, NIH/3T3 cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:1000-1:3000 |
Sample-dependent, check data in validation data gallery |
Product Information
66771-1-Ig targets SLC25A1 in WB,ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse / IgG3 |
Class | Monoclonal |
Type | Antibody |
Immunogen | SLC25A1 fusion protein Ag7520 |
Full Name | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 |
Calculated molecular weight | 34 kDa |
Observed molecular weight | 34 kDa |
GenBank accession number | BC004980 |
Gene symbol | SLC25A1 |
Gene ID (NCBI) | 6576 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 has been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. This antibody specifically recognized the endogenous SLC25A1; no protein was detected in cells from subjects containing two alleles with truncating mutations with this antibody. (24681808, 23561848)
Protocols
Product Specific Protocols | |
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WB protocol for SLC25A1 antibody 66771-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |