SLC25A1 Monoclonal antibody

SLC25A1 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG3

Reactivity

Human, Mouse, Rat

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

1F11A3

Cat no : 66771-1-Ig

Synonyms

Citrate transport protein, CTP, SLC20A3, SLC25A1, Tricarboxylate carrier protein



Tested Applications

Positive WB detected inJurkat cells, HEK-293 cells, HST-C6 cells, NIH/3T3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:3000
Sample-dependent, check data in validation data gallery

Product Information

66771-1-Ig targets SLC25A1 in WB,ELISA applications and shows reactivity with Human, Mouse, Rat samples.

Tested Reactivity Human, Mouse, Rat
Host / Isotype Mouse / IgG3
Class Monoclonal
Type Antibody
Immunogen SLC25A1 fusion protein Ag7520
Full Name solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
Calculated molecular weight 34 kDa
Observed molecular weight 34 kDa
GenBank accession numberBC004980
Gene symbol SLC25A1
Gene ID (NCBI) 6576
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 has been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. This antibody specifically recognized the endogenous SLC25A1; no protein was detected in cells from subjects containing two alleles with truncating mutations with this antibody. (24681808, 23561848)

Protocols

Product Specific Protocols
WB protocol for SLC25A1 antibody 66771-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols