Product Information
87846-1-PBS targets SLC28A2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 |
| Calculated Molecular Weight | 658 aa, 72 kDa |
| Observed Molecular Weight | 65-71 kDa |
| GenBank Accession Number | BC093737 |
| Gene Symbol | SLC28A2 |
| Gene ID (NCBI) | 9153 |
| RRID | AB_3745785 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | O43868 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Solute carrier family 28 member 2 (SLC28A2), also called concentrative nucleoside transporter 2 (CNT2), is found mainly in the gastrointestinal tract and kidney (PMID: 10087507). The SLC28A2 gene, which is mapped to chromosome 15q21.1 in humans, encodes a sodium/nucleoside symporter preferentially located at the apical side of polarized epithelia, thereby mediating the unidirectional uptake of sodium ions coupled with nucleosides (PMID: 29928232). SLC28A2, a sodium-dependent and purine-selective transporter, has been reported to translocate antiviral purine analogs (PMID: 36244249). SLC28A2 gene, is expressed in luminal membrane of intestine and mediates efficient transport of dietary purine nucleosides and nucleoside analog ribavirin (PMID: 30679935).
