SLC28A2 Recombinant monoclonal antibody

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• SLC28A2 Recombinant monoclonal antibody (87846-1-RR)

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  WB analysis using 87846-1-RR

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 87846-1-RR (SLC28A2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

SLC28A2 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 87846-1-RR

Clone No.253453A3

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

CNT 2, CNT2, hCNT2, HsT17153, Sodium/purine nucleoside co-transporter

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Tested Applications

• Positive WB detected in: mouse brain tissue, rat brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

87846-1-RR targets SLC28A2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
• Calculated Molecular Weight: 658 aa, 72 kDa
• Observed Molecular Weight: 65-71 kDa
• GenBank Accession Number: BC093737
• Gene Symbol: SLC28A2
• Gene ID (NCBI): 9153
• RRID: AB_3745785
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: O43868
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Solute carrier family 28 member 2 (SLC28A2), also called concentrative nucleoside transporter 2 (CNT2), is found mainly in the gastrointestinal tract and kidney (PMID: 10087507). The SLC28A2 gene, which is mapped to chromosome 15q21.1 in humans, encodes a sodium/nucleoside symporter preferentially located at the apical side of polarized epithelia, thereby mediating the unidirectional uptake of sodium ions coupled with nucleosides (PMID: 29928232). SLC28A2, a sodium-dependent and purine-selective transporter, has been reported to translocate antiviral purine analogs (PMID: 36244249). SLC28A2 gene, is expressed in luminal membrane of intestine and mediates efficient transport of dietary purine nucleosides and nucleoside analog ribavirin (PMID: 30679935).