Product Information
31867-1-PBS targets SLX4 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36095 Product name: Recombinant human BTBD12 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1530-1834 aa of BC036335 Sequence: MPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGEVSASQAAVQAADTDEALRCYIRSKPALYQKVLLYQPFELRELQAELRQNGLRVSSRRLLDFLDTHCITFTTAATRREKLQGRRRQPRGKKKVERN Predict reactive species |
| Full Name | BTB (POZ) domain containing 12 |
| Calculated Molecular Weight | 1834 aa, 200 kDa |
| Observed Molecular Weight | 180-200 kDa |
| GenBank Accession Number | BC036335 |
| Gene Symbol | BTBD12 |
| Gene ID (NCBI) | 84464 |
| RRID | AB_3742487 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q8IY92 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
SLX4 (Structure-specific endonuclease subunit SLX4) is a scaffold protein that assembles multiple structure-specific nucleases, including SLX1, MUS81-EME1, and XPF-ERCC1. These nucleases are essential for resolving complex DNA structures that arise during DNA replication, repair, and recombination (PMID: 34804132). SLX4 is a key protein involved in DNA repair and genome stability, with significant implications for genetic disorders and cancer.
