SRCRB4D Polyclonal antibody, PBS Only

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• SRCRB4D Polyclonal antibody, PBS Only (11350-1-PBS)

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  WB analysis using 11350-1-AP (same clone as 11350-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11350-1-AP (SRCRB4D antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11350-1-PBS in a different storage buffer formulation.

SRCRB4D Polyclonal Antibody for WB, Indirect ELISA

Cat No. 11350-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

Four scavenger receptor cysteine-rich domains-containing protein, S4D-SRCRB, Scavenger receptor cysteine-rich domain-containing group B protein, SSC4D

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Product Information

11350-1-PBS targets SRCRB4D in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag1884

  Product name: Recombinant human SRCRB4D protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-190 aa of BC015651

  Sequence: MTGTLRTRAWPAAKRAAGLRWALRDEARLSDCFHLGWGQHNCGHHEDAGALCAGEADSEGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS

• Full Name: scavenger receptor cysteine rich domain containing, group B (4 domains)
• Calculated Molecular Weight: 61 kDa
• Observed Molecular Weight: 70 kDa
• GenBank Accession Number: BC015651
• Gene Symbol: SRCRB4D
• Gene ID (NCBI): 136853
• RRID: AB_3741817
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8WTU2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SRCRB4D (also known as SSC4D or S4D-SRCRB) is a soluble, secreted pattern-recognition receptor belonging to the scavenger receptor cysteine-rich (SRCR) superfamily, characterized by four group B SRCR domains. It is broadly expressed in epithelial cells of the kidney, placenta, liver, intestine, and lung, and functions as an innate immune sensor capable of binding diverse bacteria and protozoan parasites, thereby enhancing phagocytosis by monocytes.