CoraLite® Plus 488-conjugated THBD Monoclonal antibody

THBD Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2b






CoraLite® Plus 488 Fluorescent Dye



Cat no : CL488-67831


CD141, Fetomodulin, THBD, THRM, thrombomodulin, TM

Tested Applications

Positive IF detected inhuman lung cancer tissue

Recommended dilution

Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-67831 targets THBD in IF applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen THBD fusion protein Ag5723
Full Name thrombomodulin
Calculated molecular weight 60 kDa
Observed molecular weight105 kDa
GenBank accession numberBC035602
Gene symbol THBD
Gene ID (NCBI) 7056
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Thrombomodulin, also known as CD141, is an endothelial cell surface glycoprotein that forms a 1:1 complex with the coagulation factor thrombin and plays an important role as a natural anticoagulant. Thrombomodulin serves to convert thrombin from a procoagulant protein into the activator for protein C. Once converted to activated protein C (APC), this protein serves as a major anticoagulant in blood (PMID: 2827310). Thrombomodulin is also located in other cells (keratinocytes, osteoblasts, macrophages,...) where it might be involved in cell differentiation or in inflammation (PMID: 9814688). In humans, thrombomodulin is encoded by the THBD gene. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. Thrombomodulin is glycosylated and has an apparent molecular weight of 75 to 110 kDa (PMID: 1650405; 2827310).


Product Specific Protocols
IF protocol for CL Plus 488 THBD antibody CL488-67831Download protocol
Standard Protocols
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