Tested Applications
| Positive WB detected in | mouse brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
| IHC | See 1 publications below |
Product Information
24092-1-AP targets TMEM201 in WB, IHC, ELISA applications and shows reactivity with mouse samples.
| Tested Reactivity | mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag21360 Product name: Recombinant human TMEM201 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 22-218 aa of BC137291 Sequence: VTACAAAGVLLYRIARRMKPTHTMVNCWFCNQDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYLEHLNHVVSSAPSLRDPSQPQQWVSSQVLLCKRCNHHQTTKIKQLAAFAPREEGRYDEEVEVYRHHLEQMYKLCRPCQAAVEYYIKHQNRQLRALLLSHQFKRREADQTHAQNFSSAVKSPVQVILLR Predict reactive species |
| Full Name | transmembrane protein 201 |
| Calculated Molecular Weight | 666 aa, 72 kDa |
| Observed Molecular Weight | 43 kDa |
| GenBank Accession Number | BC137291 |
| Gene Symbol | TMEM201 |
| Gene ID (NCBI) | 199953 |
| RRID | AB_2879430 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | Q5SNT2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TMEM201, also known as SAMP1 and NET5, is a member of the TMEM201 family. TMEM201 is a nuclear envelope transmembrane protein primarily localized to the inner nuclear membrane. It plays a crucial role in nuclear envelope architecture and is a component of the linker of nucleoskeleton and cytoskeleton (LINC) complex. TMEM201 is essential for proper nuclear division and nuclear membrane reorganization during mitosis (PMID: 35311970, PMID: 35311970).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TMEM201 antibody 24092-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Int J Mol Sci Characterization of the Clinical Significance and Immunological Landscapes of a Novel TMEMs Signature in Hepatocellular Carcinoma and the Contribution of TMEM201 to Hepatocarcinogenesis
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