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URAT1 Polyclonal antibody, PBS Only (14937-1-PBS)

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WB analysis using 14937-1-AP (same clone as 14937-1-PBS)
Various lysates were subjected to SDS PAGE followed by western blot with 14937-1-AP (URAT1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.
WB analysis of pig kidney using 14937-1-AP (same clone as 14937-1-PBS)
pig kidney tissue were subjected to SDS PAGE followed by western blot with 14937-1-AP (URAT1 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.
IHC staining of mouse kidney using 14937-1-AP (same clone as 14937-1-PBS)
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.
IHC staining of mouse kidney using 14937-1-AP (same clone as 14937-1-PBS)
Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.
IHC staining of human kidney using 14937-1-AP (same clone as 14937-1-PBS)
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.
IHC staining of human kidney using 14937-1-AP (same clone as 14937-1-PBS)
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

Featured Product
KD/KO Validated

URAT1 Polyclonal antibody, PBS Only

Name: URAT1 Polyclonal antibody, PBS Only
Brand: Proteintech
SKU: 14937-1-PBS

URAT1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 14937-1-PBS

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, pig

Applications

WB, IHC, Indirect ELISA

Synonyms

SLC22A12, OAT4L, OATL4, Organic anion transporter 4-like protein, Renal specific transporter

Formulation: PBS Only

PBS, Azide, Glycerol

Conjugate: Unconjugated

Size/Concentration:

-/ -

Freight/Packing: -

Quantity

- +

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

14937-1-PBS targets URAT1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Reactivity	human, mouse, rat, pig
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag6770 Product name: Recombinant human URAT1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 4-351 aa of BC053348 Sequence: SELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTC Predict reactive species
Full Name	solute carrier family 22 (organic anion/urate transporter), member 12
Calculated Molecular Weight	60 kDa
Observed Molecular Weight	65-70 kDa, 40 kDa
GenBank Accession Number	BC053348
Gene Symbol	URAT1
Gene ID (NCBI)	116085
RRID	AB_2191270
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	Q96S37
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

Human urate anion exchanger (URAT1), also known as SLC22A12, is a urate transporter located in the proximal tubules of human kidney and responsible for urate reabsorption. Defects in gene encoding URAT1 cause hypouricemia renal type 1 (RHUC1). This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40kDa protein.