UTP18 Polyclonal antibody, PBS Only

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• UTP18 Polyclonal antibody, PBS Only (31055-1-PBS)

• 

  WB analysis using 31055-1-AP (same clone as 31055-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31055-1-AP (UTP18 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31055-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 31055-1-AP (same clone as 31055-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31055-1-AP (UTP18 antibody) at dilution of 1:40000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31055-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 31055-1-AP (same clone as 31055-1-PBS)

  WB result of UTP18 antibody (31055-1-AP; 1:20000; incubated at room temperature for 1.5 hours) with sh-Control and sh-UTP18 transfected HeLa cells. This data was developed using the same antibody clone with 31055-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

UTP18 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31055-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

CGI 48, WDR50

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Product Information

31055-1-PBS targets UTP18 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag34662

  Product name: Recombinant human UTP18 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 72-205 aa of NM_016001

  Sequence: RNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLRGPRVQEHEDSGDSEVENEAKGNFPPQKKPVWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQHAMGGVPAWAETTKRKTS

• Full Name: UTP18, small subunit (SSU) processome component, homolog (yeast)
• Calculated Molecular Weight: 62 kDa
• Observed Molecular Weight: 62 kDa
• GenBank Accession Number: NM_016001
• Gene Symbol: UTP18
• Gene ID (NCBI): 51096
• RRID: AB_3669835
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9Y5J1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

UTP18 (UTP18 small subunit processome component), also known as WDR50. It is expected to be located in nucleus. The protein is one part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. The calculated molecular weight of UTP18 is 62 kDa.