Validation Data Gallery
Product Information
CL647-IFNg is a recombinant CoraLite ® Plus 647 conjugated anti IFNg Nanobody (VHH) that targets IL6 in IF and FC applications, showing reactivity with human samples.
| Applications | IF, FC |
| Reactivity | Human |
| Conjugate | CoraLite® Plus 647 |
| Type | Nanobody |
| Class | Recombinant |
| Host | Alpaca |
| Affinity | Picomolar range, below the assay limit (biolayer interferometry) |
| Molecular Weight | 14.8 kDa |
| Form | Liquid |
| Excitation/Emission Maxima Wavelengths | 654 nm / 674 nm |
| RRID | AB_3665386 |
| Storage Buffer | 10 mM HEPES pH 7.0, 500 mM NaCl, 5 mM EDTA, 0.09% sodium azide |
| Storage Condition | Store at -20°C |
| Shipping | blue ice |
| Background | IFN gamma (IFNG) is a soluble cytokine that is the only member of the type II class of IFN. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). |