APOA1 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66206-1-Ig |CloneNo.: 1C9G5

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Freight/Packing

Con: 160 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human plasma tissue

Positive IHC detected in:
human liver cancer tissue, human liver cancer tissue, mouse kidney tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
apolipoprotein A-I

Calculated molecular weight:
31 kDa

Observed molecular weight:
26-28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
APOA1

Synonyms
Apo AI, ApoA I, APOA1, apolipoprotein A I, Apolipoprotein A1
Background

ApoA1 is a major protein component of high density lipoproteins (HDL) which is associated with reversed cholesterol transport, lipid/cholesterol binding, lecithin/cholesterol acyltransferase (LCAT) activation and specific receptors binding. It is synthesized in the liver and small intestine. Defects of ApoA1 cause low HDL level and systemic non-neuropathic amyloidosis. Serum concentration of ApoA1 is inversely related to the risk of developing atherosclerosis. This antibody was generated against the C-terminal region of human ApoA1.


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