GCLM Antibody 14 Publications

Rabbit Polyclonal| Catalog number: 14241-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, A431 cells, K-562 cells, L02 cells, MCF-7 cells

Positive IP detected in:
A431 cells

Positive IHC detected in:
human liver cancer tissue, human liver cancer tissue, human skeletal muscle tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutamate-cysteine ligase, modifier subunit

Calculated molecular weight:
31 kDa

Observed molecular weight:
31 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GCLM

Synonyms
Gamma ECS regulatory subunit, GCLM, GCS light chain, GLCLR
Background

GCLM(Glutamate--cysteine ligase regulatory subunit) is also named as GLCLR and belongs to the aldo/keto reductase family. It catalyzes the first step of GSH synthesisand is involved in gamma-glutamyl cycle. GCLM is implicated in some forms of hemolytic anemia.


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