N-cadherin Antibody 36 Publications

Rabbit Polyclonal| Catalog number: 13769-1-AP

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Freight/Packing

Con: 48 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, mouse heart tissue

Positive IHC detected in:
human heart tissue, human heart tissue, mouse brain tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cadherin 2, type 1, N-cadherin (neuronal)

Calculated molecular weight:
906aa,100 kDa

Observed molecular weight:
90 kDa,140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDH2

Synonyms
Background

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619).


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