Product Information
85835-4-PBS targets MBL as part of a matched antibody pair:
MP02145-1: 85835-4-PBS capture and 85835-3-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
CatNo: Eg3157 Product name: Recombinant Mouse Mbl2 protein (rFc Tag) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 19-244 aa of NM_010776.1 Sequence: ETLTEGVQNSCPVVTCSSPGLNGFPGKDGRDGAKGEKGEPGQGLRGLQGPPGKVGPTGPPGNPGLKGAVGPKGDRGDRAEFDTSEIDSEIAALRSELRALRNWVLFSLSEKVGKKYFVSSVKKMSLDRVKALCSEFQGSVATPRNAEENSAIQKVAKDIAYLGITDVRVEGSFEDLTGNRVRYTNWNDGEPNNTGDGEDCVVILGNGKWNDVPCSDSFLAICEFSD Predict reactive species |
| Full Name | mannose-binding lectin (protein C) 2 |
| Calculated Molecular Weight | 26 kDa |
| Observed Molecular Weight | 32 kDa |
| GenBank Accession Number | NM_010776.1 |
| Gene Symbol | Mbl2 |
| Gene ID (NCBI) | 17195 |
| RRID | AB_3744411 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P41317 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Mannan-binding lectin (MBL) is a calcium-dependent (type C) serum lectin protein that is synthesized in the liver and circulates in the blood. It plays the role of a pattern recognition receptor in the innate immune system. It can recognize the carbohydrate structures on the surface of microorganisms and activate the lectin complement pathway through serine proteases related to mannan-binding lectins (MASPs), thereby achieving phagocytosis and inflammatory responses without the involvement of antibodies.(PMID: 16948640; 16395391)
