CoraLite® Plus 488-conjugated AGR2 Monoclonal antibody
AGR2 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Pig
Applications
IF
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
1A8A8
Cat no : CL488-66768
Synonyms
Validation Data Gallery
Tested Applications
Positive IF detected in | HT-29 cells, human colon cancer tissue |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Product Information
CL488-66768 targets AGR2 in IF applications and shows reactivity with Human, Pig samples.
Tested Reactivity | Human, Pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | AGR2 fusion protein Ag2919 |
Full Name | anterior gradient homolog 2 (Xenopus laevis) |
Calculated molecular weight | 175 aa, 20 kDa |
Observed molecular weight | 17 kDa |
GenBank accession number | BC015503 |
Gene symbol | AGR2 |
Gene ID (NCBI) | 10551 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 AGR2 antibody CL488-66768 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |