CoraLite®488-conjugated AGR2 Monoclonal antibody

AGR2 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2b

Reactivity

Human, Pig

Applications

IF

Conjugate

CoraLite®488 Fluorescent Dye

CloneNo.

1A8A8

Cat no : CL488-66768

Synonyms

AG 2, AG2, AGR2, GOB 4, HAG 2, HPC8, PDIA17, XAG 2



Tested Applications

Positive IF detected inHT-29 cells
For other applications, we recommend the unconjugated version of this antibody, 66768-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL488-66768 targets AGR2 in IF applications and shows reactivity with Human, Pig samples.

Tested Reactivity Human, Pig
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen AGR2 fusion protein Ag2919
Full Name anterior gradient homolog 2 (Xenopus laevis)
Calculated molecular weight 175 aa, 20 kDa
Observed molecular weight 17 kDa
GenBank accession numberBC015503
Gene symbol AGR2
Gene ID (NCBI) 10551
Conjugate CoraLite®488 Fluorescent Dye
Excitation/Emission maxima wavelengths488 nm/515 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.

Protocols

Product Specific Protocols
IF protocol for CL488 AGR2 antibody CL488-66768Download protocol
Standard Protocols
Click here to view our Standard Protocols