CoraLite®594-conjugated ALDH1A1 Monoclonal antibody
ALDH1A1 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
human, mouse, rat, pig
CoraLite®594 Fluorescent Dye
Cat no : CL594-60171
|Positive IF detected in||HeLa cells|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
CL594-60171 targets ALDH1A1 in IF applications and shows reactivity with human, mouse, rat, pig samples.
|Tested Reactivity||human, mouse, rat, pig|
|Host / Isotype||Mouse / IgG1|
|Immunogen||ALDH1A1 fusion protein Ag8551|
|Full Name||aldehyde dehydrogenase 1 family, member A1|
|Calculated molecular weight||501 aa, 55 kDa|
|GenBank accession number||BC001505|
|Gene ID (NCBI)||216|
|Conjugate||CoraLite®594 Fluorescent Dye|
|Excitation/Emission maxima wavelengths||588 nm / 604 nm|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.|
|Storage Conditions||Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
ALDH1A1(Aldehyde dehydrogenase family 1 member A1 ), also named as ALDC, ALDH1 and PUMB1, belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase, an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells(PMID:19296407). And it is important for multiple biological activities including drug resistance, cell differentiation, and oxidative stress response(PMID:19025616). As a novel cancer stem cell marker, ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1A1 in relatively restricted or limited levels such as breast, lung, ovarian or colon cancer(PMID: 20422001). This antibody is CL594(Ex/Em 593 nm/614 nm) conjugated.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Vanessa (Verified Customer) (10-12-2023)
Tried many times different concentrations (until 1:50) and no signal.