CoraLite®594-conjugated AP5Z1/SPG48 Monoclonal antibody

AP5Z1/SPG48 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

1G1D7

Cat no : CL594-66533

Synonyms

KIAA0415, SPG48



Tested Applications

Positive IF detected inHEK-293 cells
For other applications, we recommend the unconjugated version of this antibody, 66533-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL594-66533 targets AP5Z1/SPG48 in IF applications and shows reactivity with Human, rat samples.

Tested Reactivity Human, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen AP5Z1/SPG48 fusion protein Ag26961
Full Name KIAA0415
Calculated molecular weight 807 aa, 88 kDa
Observed molecular weight 88 kDa, 160 kDa
GenBank accession numberBC037399
Gene symbol KIAA0415
Gene ID (NCBI) 9907
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths593 nm/614 nm
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

AP5Z1, also known as SPG48 and KIAA0415, is a part of AP-5. Biallelic mutations in the AP5Z1 gene encoding the AP5Z1 subunit have been described in a small number of patients with hereditary spastic paraplegia (HSP). AP5Z1 physically interacts with other HSP proteins and that patient cells are sensitive to DNA damaging drugs.

Protocols

Product Specific Protocols
IF protocol for CL594 AP5Z1/SPG48 antibody CL594-66533Download protocol
Standard Protocols
Click here to view our Standard Protocols