ARHGEF16 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10153-2-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse kidney tissue

Positive IHC detected in:
human pancreas cancer tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Rho guanine exchange factor (GEF) 16

Calculated molecular weight:
80 kDa

Observed molecular weight:
80 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARHGEF16

Synonyms
ARHGEF16, GEF16, NBR
Background

Small GTPases of the Rho family are critical regulators of various cellular functions including actin cytoskeleton organization, activation of kinase cascades, mitogenesis, transcriptional activation and stimulation of DNA synthesis. Rho proteins cycle between a biologically active GTP-bound state and an inactive GDP-bound state. Rho guanine nucleotide exchange factor (GEF) has a crucial role in activating small GTPase by exchange GDP for GTP. ARGEF16 is one of the multiple GEF members. Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.


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