CBX3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66446-1-Ig |CloneNo.: 1A5A3

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
NIH/3T3 cells, HEK-293 cells, HeLa cells, Jurkat cells, RAW 264.7 cells

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:2000-1:20000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chromobox homolog 3 (HP1 gamma homolog, Drosophila)

Calculated molecular weight:
21 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CBX3

Synonyms
CBX3, Chromobox protein homolog 3, HECH, HP1 GAMMA, HP1Hs gamma, Modifier 2 protein
Background

The family of Heterochromatin protein 1 (HP1) proteins is a family of highly conserved heterochromatin-associated non-histone chromosomal proteins , which has important functions in nucleus. These functions include gene activation or repression, regulation of binding of cohesion complexes to centromere, sequestration of genes to nuclear periphery, and heterochromatin formation and propagation. Much evidence shows that HP1 proteins interact with numerous proteins including methylated histones, histone methyltransferases and so on. CBX3 is one of the paralogues of HP1 proteins


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