|Positive WB detected in
|NIH/3T3 cells, HEK-293 cells, HeLa cells, Jurkat cells, RAW 264.7 cells
|Positive IF detected in
|Western Blot (WB)
|WB : 1:2000-1:20000
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
66446-1-Ig targets CBX3 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.
|Host / Isotype
|Mouse / IgG2a
|CBX3 fusion protein Ag19112
|chromobox homolog 3 (HP1 gamma homolog, Drosophila)
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Protein A purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
The family of Heterochromatin protein 1 (HP1) proteins is a family of highly conserved heterochromatin-associated non-histone chromosomal proteins , which has important functions in nucleus. These functions include gene activation or repression, regulation of binding of cohesion complexes to centromere, sequestration of genes to nuclear periphery, and heterochromatin formation and propagation. Much evidence shows that HP1 proteins interact with numerous proteins including methylated histones, histone methyltransferases and so on. CBX3 is one of the paralogues of HP1 proteins
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
ILIAS (Verified Customer) (05-26-2023)
The 66446-1-Ig worked very well in both Western Blot and Immunofluorescence microscopy experiments