CD3 Fusion Protein

Catalog number: 60181-1-Ig
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279.0000

Freight/Packing £00.00

Size: 09µ/gram

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Product Name:
CD3 Mouse Monoclonal antibody

Catalog No:
60181-1-Ig

Source:
E. coli-derived, {{ptg:Vector}}

Peptide Sequence:
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({{ptg:AntigenPeptide}} encoded by BC049847)

Activity:
Not tested.

Endotoxin Level:
Please contact the lab for more information.
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Formulation:
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Reconstitution:
Reconstitute at {{ptg:SizeDesc}} sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage (see Stability and Storage for more details).
If a different concentration is needed for your purposes please adjust the reconstitution volume as required (please note: the ion concentration of the final solution will vary according to the volume used).
Note: Centrifuge vial before opening. When reconstituting, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution.

Shipping:
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Stability and Storage:
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Storage of Reconstituted Protein:
Short-term storage: Store at 2-8°C for two weeks.
Long-term storage: Aliquot and store at -20°C to -80°C for up to 6 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Background

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of human CD3 molecule.


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