CoraLite®594 Anti-Mouse CD64 Rabbit Recombinant Antibody

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  FC experiment of mouse bone marrow cells using CL594-98218

  1x10^6 mouse bone marrow cells were surface stained with FITC Plus Anti-Mouse CD11b, and 0.25 ug CoraLite®594 Anti-Mouse CD64 Rabbit RecAb (CL594-98218, Clone:241809A6) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using CL594-98218

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug CoraLite®594 Anti-Mouse CD64 Rabbit RecAb (CL594-98218, Clone: 241809A6)(red) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were not fixed.

CD64 Uni-rAb^TM Recombinant Antibody for FC

Cat No. CL594-98218

Clone No.241809A6

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

High affinity immunoglobulin gamma Fc receptor I, FcRI, Fcgr1, Fc-gamma RI, Fcg1

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Tested Applications

• Positive FC detected in: mouse bone marrow cells

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-98218 targets CD64 in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: Fc receptor, IgG, high affinity I
• Calculated Molecular Weight: 45 kDa
• GenBank Accession Number: NM_010186.5
• Gene Symbol: Fcgr1
• Gene ID (NCBI): 14129
• Conjugate: CoraLite®594 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 588 nm / 604 nm
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P26151
• Storage Buffer: PBS with 0.09% sodium azide.
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses.