CoraLite® Plus 488-conjugated Cyclin B2 Monoclonal antibody

Cyclin B2 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2a


Human, mouse




CoraLite® Plus 488 Fluorescent Dye



Cat no : CL488-67726


CCNB2, cyclin B2, G2/mitotic specific cyclin B2, HsT17299

Tested Applications

Positive IF detected inmouse testis tissue

Recommended dilution

Immunofluorescence (IF)IF : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-67726 targets Cyclin B2 in IF applications and shows reactivity with Human, mouse samples.

Tested Reactivity Human, mouse
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen Cyclin B2 fusion protein Ag16329
Full Name cyclin B2
Calculated Molecular Weight 398 aa, 45 kDa
GenBank Accession NumberBC105086
Gene Symbol CCNB2
Gene ID (NCBI) 9133
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Cyclin B2 (CCNB2) is a member of cyclin family proteins, which regulate the activities of cyclin dependent kinases (CDKs) and different cyclins function spatially and temporally in specific phases of the cell cycle. Cyclin B2 serves a key role in progression of G2/M transition. Cyclin B2 has been found to be up-regulated in a variety of human cancers, such as adrenocortical carcinoma, breast carcinoma, colorectal adenocarcinoma, pituitary adenoma and gastric cancer. The aberrant expression of Cyclin B2 deregulates spindle checkpoints in the cell cycle and results in chromosomal instability (CIN), one of the signature phenotypes of most cancers. Moreover, serum circulating Cyclin B2 mRNA expression has been found increased in cancer patients and associated with cancer stage and metastasis status.


Product Specific Protocols
IF protocol for CL Plus 488 Cyclin B2 antibody CL488-67726Download protocol
Standard Protocols
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