Tested Applications
| Positive IF/ICC detected in | HeLa cells |
| Positive FC (Intra) detected in | HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
CL488-17516 targets Cytokeratin 17-Specific in IF/ICC, FC (Intra) applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | keratin 17 |
| Calculated Molecular Weight | 48 kDa |
| GenBank Accession Number | NM_000422 |
| Gene Symbol | Cytokeratin 17 |
| Gene ID (NCBI) | 3872 |
| RRID | AB_2919152 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q04695 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. Keratin 17 is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. It is used as a marker for trauma. This antibody is specifically against KRT17.
Protocols
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 488 Cytokeratin 17-Specific antibody CL488-17516 | Download protocol |
| IF protocol for CL Plus 488 Cytokeratin 17-Specific antibody CL488-17516 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The Cytokeratin 17-Specific Polyclonal antibody (CL488-17516) has 1 citation. It appears in Cancer Cell (IF 56.1), published in 2026. The study investigates a conserved re-epithelialization program underlying malignancy in pancreatic ductal adenocarcinoma, placing the research in the fields of cancer biology and epithelial cell dynamics. The antibody was applied in immunofluorescence (IF) on human samples.
| Species | Application | Title |
|---|---|---|
Cancer Cell A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma. |
