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- KD/KO Validated
CoraLite®555-conjugated G3BP1 Monoclonal antibody
G3BP1 Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
Human, mouse, rat, pig
CoraLite®555 Fluorescent Dye
Cat no : CL555-66486
|Positive IF detected in
|sodium arsenite treated HeLa cells
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL555-66486 targets G3BP1 in IF applications and shows reactivity with Human, mouse, rat, pig samples.
|Human, mouse, rat, pig
|Host / Isotype
|Mouse / IgG1
|G3BP1 fusion protein Ag3728
|GTPase activating protein (SH3 domain) binding protein 1
|Calculated molecular weight
|466 aa, 52 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite®555 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|557 nm / 570nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
GAP SH3 Binding Protein 1 (G3BP1), also named as G3BP, is an effector of stress granule (SG) assembly. SG biology plays an important role in the pathophysiology of TDP-43 in ALS and FTLD-U. G3BP1 can be used as a marker of SG. It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. G3BP1 has recently been implicated in cancer biology.