GOLGA2/GM130 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 11308-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, human spleen tissue

Positive IHC detected in:
human testis tissue, human kidney tissue, human placenta tissue, human testis tissue

Positive IF detected in:
HepG2 cells, HEK-293 cells

Positive FC detected in:
HEK-293 cells

Recommended dilution:
WB : 1:2000-1:12000
IHC : 1:50-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
golgi autoantigen, golgin subfamily a, 2

Calculated molecular weight:
111 kDa

Observed molecular weight:
130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GOLGA2

Synonyms
GM130, GM130 autoantigen, GOLGA2, Golgin 95, Golgin subfamily A member 2
Background

GOLGA2, also known as GM130, is a 130 kDa cis-Golgi matrix protein which is one component of the detergent and salt resistant Golgi matrix. It is a peripheral membrane protein highly bound to Golgi membrane and localized mainly at the cytoplasmic face of cis-Golgi membrane. Together with its interacting partner proteins, including p115, giantin, GRASP65, and Rab GTPase, GOLGA2/GM130 is involved in the regulation of ER-to-Golgi transport and also in the maintenance of the Golgi structure. Emerging evidence suggest that the GOLGA2/GM130 has potential roles in the control of glycosylation, cell cycle progression, and higher order cell functions such as cell polarization and directed cell migration. (PMID: 20197635)


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