- Featured Product
- KD/KO Validated
CoraLite®594-conjugated Glutamine Synthetase Monoclonal antibody
Glutamine Synthetase Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse, Rat
Applications
IF
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
1B6G4
Cat no : CL594-66323
Synonyms
Validation Data Gallery
Tested Applications
Positive IF detected in | mouse brain tissue |
Recommended dilution
Application | Dilution |
---|---|
Immunofluorescence (IF) | IF : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Product Information
CL594-66323 targets Glutamine Synthetase in IF applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Glutamine Synthetase fusion protein Ag6309 |
Full Name | glutamate-ammonia ligase (glutamine synthetase) |
Calculated molecular weight | 374 aa, 42 kDa |
GenBank accession number | BC011700 |
Gene symbol | GLUL |
Gene ID (NCBI) | 2752 |
Conjugate | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
GLUL(Glutamine synthetase) is also named as GS,GLNS and belongs to the glutamine synthetase family.This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for proliferation of fetal skin fibroblasts(PMID:18662667).Defects in GLUL are the cause of congenital systemic glutamine deficiency (CSGD).Organismal glutamine production is augmented secondary to an increase in the activity of glutamine synthetase in the lung and skeletal muscle(PMID:7630137). The antibody is conjugated with CL594, Ex/Em 593 nm/614 nm.
Protocols
Product Specific Protocols | |
---|---|
IF protocol for CL594 Glutamine Synthetase antibody CL594-66323 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |