MDH1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 15904-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HL-60 cells, HepG2 cells, human kidney tissue, human spleen tissue, mouse liver tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human renal cell carcinoma tissue, human liver cancer tissue, human renal cell carcinoma tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
malate dehydrogenase 1, NAD (soluble)

Calculated molecular weight:
334aa,36 kDa

Observed molecular weight:
36 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MDH1

Synonyms
Cytosolic malate dehydrogenase, MDH s, MDH1, MDHA, MOR2
Background

MDH1(Malate dehydrogenase, cytoplasmic) is also named as MDHA and belongs to the LDH/MDH superfamily and MDH type 2 family which catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. It can exsit as a dimer and the dimeric MDH1 is the mitochondrial isoenzyme, whereas the tetrameric MDH2 is the glycosomal isoenzyme.(PMID:10693743).


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