CoraLite® Plus 647-conjugated TGF beta 1 Monoclonal antibody
TGF beta 1 Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
CoraLite® Plus 647 Fluorescent Dye
Cat no : CL647-69012
|Positive FC detected in
|Flow Cytometry (FC)
|FC : 0.40 ug per 10^6 cells in a 100 µl suspension
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL647-69012 targets TGF beta 1 in FC (Intra) applications and shows reactivity with Human samples.
|Host / Isotype
|Mouse / IgG1
|TGF beta 1 fusion protein HZ-1011
|transforming growth factor, beta 1
|Gene ID (NCBI)
|CoraLite® Plus 647 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|654 nm / 674 nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).
This antibody is used to Block/Neutralize TGF beta 1 protein.