CoraLite®594-conjugated Phospho-GSK3B (Ser9) Monoclonal antibody
Phospho-GSK3B (Ser9) Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
CoraLite®594 Fluorescent Dye
Cat no : CL594-67558
|Positive FC detected in
|Calyculin A treated PC-3 cells
|Flow Cytometry (FC)
|FC : 0.13 ug per 10^6 cells in a 100 µl suspension
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL594-67558 targets Phospho-GSK3B (Ser9) in FC (Intra) applications and shows reactivity with Human samples.
|Host / Isotype
|Mouse / IgG1
|glycogen synthase kinase 3 beta
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite®594 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|588 nm / 604 nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to INS regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .