- Featured Product
- KD/KO Validated
CoraLite®594-conjugated RAB27A Monoclonal antibody
RAB27A Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
CoraLite®594 Fluorescent Dye
Cat no : CL594-66058
|Positive IF detected in
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
The immunogen of CL594-66058 is RAB27A Fusion Protein expressed in E. coli.
|Host / Isotype
|Mouse / IgG1
|RAB27A fusion protein Ag12382
|RAB27A, member RAS oncogene family
|Calculated molecular weight
|221 aa, 25 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite®594 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|588 nm / 604 nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Rab27a is a member of a large family of Ras-related small GTPases. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Recent studies suggest that Rab27a is associated with melanosomes in pigmented cells and regulates melanosome transport via its interaction with actin-based cellular motors such as myosin Va and myosin VIIa. RAB27A is also required for regulated secretion in cytotoxic T lymphocytes. Rab27a is implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal.