CoraLite® Plus 488-conjugated TOLLIP Monoclonal antibody

TOLLIP Monoclonal Antibody for

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, rat

Applications

Conjugate

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1B3C4

Cat no : CL488-68170

Synonyms

FLJ33531, IL 1RAcPIP, toll interacting protein, TOLLIP



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-68170 targets TOLLIP in applications and shows reactivity with Human, mouse, rat samples.

Tested Reactivity Human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TOLLIP fusion protein Ag32731
Full Name toll interacting protein
Calculated Molecular Weight 30 kDa
Observed Molecular Weight30 kDa
GenBank Accession NumberBC012057
Gene Symbol TOLLIP
Gene ID (NCBI) 54472
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TOLLIP (Toll interacting protein), is an inhibitory adaptor protein. Tollip is a negative regulator of IL-1R and Toll-like receptors signalling pathway, involved in inflammatory immune response and inhibiting IRAK1 phosphorylation and kinase activity (PMID:11441107, PMID:10854325, PMID:11751856). The TOLLIP-dependent selective autophagy pathway plays a role in clearance of cytotoxic polyQ proteins aggregates (PubMed:25042851).

Protocols

Product Specific Protocols
FC protocol for CL Plus 488 TOLLIP antibody CL488-68170Download protocol
Standard Protocols
Click here to view our Standard Protocols