Tested Applications
Positive FC (Intra) detected in | Transfected Vero |
Recommended dilution
Application | Dilution |
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Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.4 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL488-85780-2 targets dsRNA in FC (Intra), ELISA applications and shows reactivity with n/a samples.
Tested Reactivity | n/a |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | dsRNA |
Gene Symbol | |
Gene ID (NCBI) | |
Conjugate | CoraLite®488 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 491 nm / 516 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
dsRNA is formed by the base pairing of two RNA strands, creating a double helix structure similar to DNA, but with some differences. dsRNA can be generated through various mechanisms. In the context of viral infections, it can be derived from the genomes of dsRNA viruses, replication intermediates of single-stranded RNA viruses, or bidirectional transcription of certain DNA viruses. Additionally, aberrant splicing or transcriptional processes may lead to the formation of dsRNA structures. dsRNA is recognized as a pathogen-associated molecular pattern (PAMP) by the immune system. It can trigger a series of immune responses in cells, including the activation of antiviral innate immune pathways.
Protocols
Product Specific Protocols | |
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FC protocol for CL488 dsRNA antibody CL488-85780-2 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |