FITC Anti-Mouse CD107b (ABL-93)

CD107b Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2a

Reactivity

Mouse

Applications

FC (Intra)

Conjugate

FITC Fluorescent Dye

CloneNo.

ABL-93

Cat no : FITC-65052

Synonyms

CD107b, Lamp 2, Lamp 2a, Lamp 2b, Lamp 2c, Lamp2, Mac3



Tested Applications

Positive FC detected inNIH/3T3 cells

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

FITC-65052 targets CD107b in FC (Intra) applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Host / Isotype Rat / IgG2a
Class Monoclonal
Type Antibody
Immunogen Glycoproteins purified from BALB/c mouse embryo 3T3 cell line
Full Name lysosomal-associated membrane protein 2
GenBank accession numberBC138718
Gene symbol Lamp2
Gene ID (NCBI) 16784
Conjugate FITC Fluorescent Dye
Excitation/Emission maxima wavelengths494 nm / 520 nm
Form Liquid
Purification Method Affinity purification
Storage Buffer PBS with 0.1% sodium azide.
Storage ConditionsStore at 2-8°C. Avoid exposure to light.

Background Information

LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis (PMID 9426697).

Protocols

Product Specific Protocols
FC protocol for FITC CD107b antibody FITC-65052Download protocol
Standard Protocols
Click here to view our Standard Protocols