CoraLite® Plus 488-conjugated CRP Monoclonal antibody
CRP Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse, rat, pig
Applications
IF
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
3F10A11
Cat no : CL488-66250
Synonyms
Validation Data Gallery
Tested Applications
Positive IF detected in | human liver tissue |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Product Information
CL488-66250 targets CRP in IF applications and shows reactivity with human, mouse, rat, pig samples.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | CRP fusion protein Ag9883 |
Full Name | C-reactive protein, pentraxin-related |
Calculated molecular weight | 224 aa, 25 kDa |
Observed molecular weight | 27 kDa |
GenBank accession number | BC020766 |
Gene symbol | CRP |
Gene ID (NCBI) | 1401 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 CRP antibody CL488-66250 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |