CoraLite® Plus 647-conjugated GSK3B Monoclonal antibody
GSK3B Monoclonal Antibody for FC (Intra)
Host / Isotype
Mouse / IgG1
CoraLite® Plus 647 Fluorescent Dye
Cat no : CL647-67329
|Positive FC detected in
|Flow Cytometry (FC)
|FC : 0.20 ug per 10^6 cells in a 100 µl suspension
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL647-67329 targets GSK3B in FC (Intra) applications and shows reactivity with Human, Pig samples.
|Host / Isotype
|Mouse / IgG1
|GSK3B fusion protein Ag17320
|glycogen synthase kinase 3 beta
|Calculated molecular weight
|433 aa, 48 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 647 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|654 nm / 674 nm
|Protein G purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Researches showed that the crystal structure of human GSK3B, expressed in insect cells, at 2.8-angstrom resolution .