JTV1 Monoclonal antibody
JTV1 Monoclonal Antibody for IHC, WB,ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, mouse, rat
Applications
WB, IHC,ELISA
Conjugate
Unconjugated
CloneNo.
1D6B5
Cat no : 66848-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HeLa cells, Jurkat cells |
Positive IHC detected in | mouse testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:2000-1:10000 |
Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
Sample-dependent, check data in validation data gallery |
Product Information
66848-1-Ig targets JTV1 in WB, IHC,ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | JTV1 fusion protein Ag0675 |
Full Name | JTV1 gene |
Calculated molecular weight | 36 kDa |
Observed molecular weight | 32-36 kDa |
GenBank accession number | BC002853 |
Gene symbol | JTV1 |
Gene ID (NCBI) | 7965 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
JTV1, also named p38, AIMP2, was first knew as a factor associated with macromolecular protein complex, which consists several different aminoacyl-tRNA synthetases. JTV1 is a scaffold protein required for the assembly and stability of the multi-tRNA synthetase complex. JTV1 could act as a mediator of TGF-beta signaling and its functional importance in the control of MYC during lung differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Protocols
Product Specific Protocols | |
---|---|
WB protocol for JTV1 antibody 66848-1-Ig | Download protocol |
IHC protocol for JTV1 antibody 66848-1-Ig | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |