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Beta Galactosidase Antibody

Beta-galactosidase: An essential enzyme

Beta-galactosidase: An essential enzyme


Overview

Beta-galactosidase, also known as beta-Gal or GLB1, is an essential enzyme that hydrolyzes beta-galactosides into monosaccharides. It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.

Antibody Type Catalog number Applications Citations
Beta-galactosidase Rabbit polyclonal 15518-1-AP ELISA, WB, IF, IHC 6
View the Beta-galactosidase product page here
 Beta Galactosidase  
Immunofluorescent analysis of Hela cells using GLB1 antibody at 1.25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red) SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 15518-1-AP(GLB1 antibody) at dilution of 1:400
Immunofluorescent analysis of Hela cells using GLB1 antibody at 1.25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 15518-1-AP(GLB1 antibody) at dilution of 1:400

GLB1 (Beta-galactosidase) is also named as ELNR1, Lactase. It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. This protein is identical to the elastin-binding protein (EBP), a major component of the nonintegrin cell surface receptor complex expressed in fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. Defects in GLB1 are the cause of GM1-gangliosidosis type 1 (GM1G1), GM1-gangliosidosis type 2 (GM1G2), GM1-gangliosidosis type 3 (GM1G3) and mucopolysaccharidosis type 4B (MPS4B).

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Resolution of the prestained protein ladder in a 10-20% Tris-glycine gel (SDS-PAGE). The image shows the migration pattern in the gel and after transfer to a PVDF membrane. Resolution of the prestained protein ladder in a 4-12% Bis-Tris gel (SDS-PAGE). The image shows the migration pattern in the gel and after transfer to a PVDF membrane.

 

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Posted:
31 March, 2020

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