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CL488-conjugated Caveolin-1 Antibody

Caveolin-1 Monoclonal Antibody for IF, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

IF, ELISA

Conjugate

CoraLite®488 Fluorescent Dye

CloneNo.

6C2B2

Cat no : CL488-66067

Synonyms

BSCL3, CAV, CAV1, Caveolin 1, CGL3, MSTP085, VIP21



Tested Applications

Positive IF detected inhuman skin cancer tissue, human liver cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 66067-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The CL488-66067 immunogen is Fusion Protein CL488-conjugated Caveolin-1 protein expressed in E. coli.

Reactivity human, mouse, rat, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Caveolin-1 fusion protein Ag8049
Full Name caveolin 1, caveolae protein, 22kDa
Calculated molecular weight 22 kDa
Observed molecular weight 20-25 kDa
GenBank accession number BC006432
Gene symbol CAV1
Gene ID (NCBI) 857
Conjugate CoraLite®488 Fluorescent Dye
Excitation/Emission maxima wavelengths488 nm/515 nm
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20oC. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

Caveolin-1 (CAV1), a multifunctional protein, is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor (PMID: 19641024). Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma (PMID: 19002186). However, other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers, especially in oral cancer (PMID: 20558341). Recent study also show that CAV1 is involved in gastric Cancer (PMID: 25339030).

Protocols

Product Specific Protocols
IF protocol for CL488-conjugated Caveolin-1 antibody CL488-66067Download protocol
Standard Protocols
Click here to view our Standard Protocols