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CoraLite® Plus 488-conjugated Caveolin-1 Monoclonal antibody
Caveolin-1 Monoclonal Antibody for FC, IF
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat, pig
Applications
IF, FC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
6C2B2
Cat no : CL488-66067
Synonyms
Validation Data Gallery
Tested Applications
Positive IF detected in | human skin cancer tissue, human liver cancer tissue |
Positive FC detected in | HeLa cells |
Recommended dilution
Application | Dilution |
---|---|
Immunofluorescence (IF) | IF : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Product Information
The immunogen of CL488-66067 is Caveolin-1 Fusion Protein expressed in E. coli.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Caveolin-1 fusion protein Ag8049 |
Full Name | caveolin 1, caveolae protein, 22kDa |
Calculated molecular weight | 22 kDa |
Observed molecular weight | 20-25 kDa |
GenBank accession number | BC006432 |
Gene symbol | CAV1 |
Gene ID (NCBI) | 857 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Caveolin-1 (CAV1), a multifunctional protein, is the main constituent molecule of caveolae and represents a scaffolding molecule for several signaling molecules including epidermal growth factor receptor (PMID: 19641024). Several studies have implicated that a reduced expression of CAV1 was found in cancers including head and neck carcinoma (PMID: 19002186). However, other studies recognize CAV1 as a tumor promoter because CAV1 is overexpressed in various kinds of cancers, especially in oral cancer (PMID: 20558341). Recent study also show that CAV1 is involved in gastric Cancer (PMID: 25339030).
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 Caveolin-1 antibody CL488-66067 | Download protocol |
FC protocol for CL Plus 488 Caveolin-1 antibody CL488-66067 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |