CoraLite®594-conjugated Fascin Monoclonal antibody
Fascin Monoclonal Antibody for FC (Intra), IF
Host / Isotype
Mouse / IgG2a
IF, FC (Intra)
CoraLite®594 Fluorescent Dye
Cat no : CL594-66321
|Positive IF detected in
|human tonsillitis tissue
|Positive FC detected in
|IF : 1:50-1:500
|Flow Cytometry (FC)
|FC : 0.20 ug per 10^6 cells in a 100 µl suspension
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL594-66321 targets Fascin in IF, FC (Intra) applications and shows reactivity with human samples.
|Host / Isotype
|Mouse / IgG2a
|Fascin fusion protein Ag6074
|fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
|Calculated molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite®594 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|588 nm / 604 nm
|Protein A purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Fascin is a highly conserved and ubiquitous actin cross-linking protein that has a major function in cell motility and adhesion. Fascin localizes to a number of highly dynamic cellular structures that require strong mechanical support which include stress fibers and cellular protrusions such as microvilli, microspikes and lamellipodia. Fascin is up-regulated in many human carcinomas. It's a marker for Reed-Sternberg cells in Hodgkin's disease; it is also a highly selective marker for dendritic cells of lymphoid tissues.