Tested Applications
| Positive WB detected in | human plasma |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
HRP-11449 targets Human IgA Heavy Chain in WB applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag2007 Product name: Recombinant human Human IgA protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 4-353 aa of BC016369 Sequence: TSPKVFPLSLCSTQPDGNVVIACLVQGFFPQEPLSVTWSESGQGVTARNFPPSQDASGDLYTTSSQLTLPATQCLAGKSVTCHVKHYTNPSQDVTVPCPVPSTPPTPSPSTPPTPSPSCCHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQGPPERDLCGCYSVSSVLPGCAEPWNHGKTFTCTAAYPESKTPLTATLSKSGNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELPREKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPLAFTQKTIDRLAGKPTHVNVSVVMAEVDGTCY Predict reactive species |
| Full Name | Human IgA Heavy Chain |
| Calculated Molecular Weight | 496 aa, 53 kDa |
| Observed Molecular Weight | 55 kDa |
| GenBank Accession Number | BC016369 |
| Gene Symbol | |
| Gene ID (NCBI) | |
| RRID | AB_2920506 |
| Conjugate | HRP |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. This antibody recognizes the Chain C region of human Ig alpha-1 (IGHA1).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for HRP Human IgA Heavy Chain antibody HRP-11449 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
HRP-11449 is a Human IgA Heavy Chain Polyclonal antibody with a total of 25 citations. The retrieved citation appears in International Journal of Chronic Obstructive Pulmonary Disease (2024), addressing cigarette smoke extract-induced mitochondrial dysfunction in bronchial epithelial cells via KLF6 silencing and SIRT4 upregulation. This places the research field in respiratory/pulmonary biology and mitochondrial function. Note: only 1 of 25 citations was retrievable in this query; additional journals and fields may be represented among the remaining citations.
| Species | Application | Title |
|---|---|---|
Int J Chron Obstruct Pulmon Dis Silencing KLF6 Alleviates Cigarette Smoke Extract-Induced Mitochondrial Dysfunction in Bronchial Epithelial Cells by SIRT4 Upregulation |
